Progress in Clinical Research on Regenerative Medicine Technologies for the Treatment of Chronic Hard-to-Heal Wounds

DOI: https://doi.org/10.62517/jmhs.202505220

Author(s)

Rui Jiao, Ronghai Zhou, Yanchun He, Decai Kong, Yiman Shen, Na Song

Affiliation(s)

People’s Hospital of Hainan District, Wuhai, Inner Mongolia Autonomous Region, China

Abstract

Regenerative medicine technologies, which activate the body’s intrinsic repair mechanisms to achieve tissue regeneration, are currently regarded as a promising new direction in the treatment of chronic hard-to-heal wounds. This study explores the clinical research progress of regenerative medicine technologies in the treatment of such wounds. Chronic hard-to-heal wounds are increasingly prevalent in China, stemming from trauma, diabetes, pressure ulcers, lower limb venous and arterial diseases, among others. The causes are complex, and treatment is challenging, leading to high disability rates and significant suffering for patients. In recent years, regenerative medicine technologies have been widely applied in the treatment of chronic hard-to-heal wounds. These technologies are capable of non-invasive liquefaction and removal of necrotic tissue, physiological control of bacterial and toxin infections, and creating a physiologically moist environment conducive to skin regeneration. By promoting cell proliferation, tissue remodeling, granulation tissue growth, angiogenesis, and epithelial migration, regenerative medicine accelerates wound healing. In the treatment of chronic hard-to-heal wounds, the application of regenerative medicine technologies helps to establish standardized treatment protocols. These protocols not only reduce the economic burden on patients but also alleviate their suffering, enhancing their quality of life and offering substantial value for clinical promotion.

Keywords

Chronic Hard-to-Heal Wounds; Regenerative Medicine Technologies; Moisture Exposed Burn Ointment; Standardized Procedures

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